VC Giant a16z Launches Spring 2025 Accelerator for Crypto Startups

Andreessen Horowitz (a16z), known for its long-term investment approach, revealed on Wednesday plans to launch its crypto startup accelerator program (CSX) in San Francisco this spring.

The firm is seeking ambitious and visionary founders to join the program and is currently accepting applications until Feb. 7.

A16z’s crypto startup accelerator offers funding, mentorship, and operational support to help early-stage startups grow and scale. As a result, many compare this initiative to Y Combinator, but specifically designed for crypto ventures. Additionally, participating founders receive capital, build connections with industry experts and collaborate with Web3 teams.

a16z Crypto Accelerator Kicks Off in April with $500K Funding and Hands-On Mentorship

Each week, the program focuses on different aspects of company-building. It starts with research and engineering, then shifts to marketing and social strategy. Next, it covers go-to-market tactics before concluding with best practices for managing people.

Founders will participate in workshops and have one-on-one sessions with experts from a16z crypto and experienced operators. Additionally, the firm promises to invest a minimum of $500,000 in each company accepted into the CSX program.

The CSX 04 program starts in April and wraps up in June with a Demo Day. During this event, each company will present their project to a crowd of top investors, industry leaders and executives from major crypto firms.

Trump’s Election Sparks Crypto Optimism

The a16z Crypto Startup Accelerator (CSX) has launched several successful startups, demonstrating the rapid innovation in the crypto and blockchain space.

AminoChain, part of the Spring 2024 cohort, is developing a decentralized marketplace for biological samples, connecting research institutions with biopharma companies. Likewise, Roux from the same cohort is revolutionizing the culinary world by turning recipes into collectible NFTs, creating new revenue opportunities for chefs and food bloggers.

Recently, the firm accepted 21 startups into its Fall 2024 cohort . This batch featured companies such as Anera Labs, Blocksense, Banyan, Cork Protocol, Future Primitive, MeshMap and zkSpin, along with several others.

Following Donald Trump’s election victory in December, the VC firm showed strong confidence, noting that the future of crypto in the US appears promising . It expects the new Trump administration to “foster innovation, accelerate progress, and enable the crypto ecosystem to thrive in the US.”